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dc.creatorBaxa, T.J.
dc.creatorHutcheson, J.P.
dc.creatorMiller, M.F.
dc.creatorBrooks, J.C.
dc.creatorNichols, W.T.
dc.creatorStreeter, M.N.
dc.creatorYates, D.A.
dc.creatorJohnson, Bradley J.
dc.date.accessioned2021-09-02T14:32:21Z
dc.date.available2021-09-02T14:32:21Z
dc.date.issued2010
dc.identifier.citationT. J. Baxa, J. P. Hutcheson, M. F. Miller, J. C. Brooks, W. T. Nichols, M. N. Streeter, D. A. Yates, B. J. Johnson, Additive effects of a steroidal implant and zilpaterol hydrochloride on feedlot performance, carcass characteristics, and skeletal muscle messenger ribonucleic acid abundance in finishing steers, Journal of Animal Science, Volume 88, Issue 1, January 2010, Pages 330–337, https://doi.org/10.2527/jas.2009-1797en_US
dc.identifier.urihttps://doi.org/10.2527/jas.2009-1797
dc.identifier.urihttps://hdl.handle.net/2346/87792
dc.descriptionThis is an open access article distributed under the terms of the Creative Commons CC BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.description.abstractThis experiment investigated the effects of zilpaterol hydrochloride (ZH) and the steroidal implant Revalor-S (RS; 120 mg of trenbolone acetate and 24 mg of estradiol-17β) on finishing steer performance and the mRNA concentration of β-adrenergic receptors (β-AR) types I and II, and types I, IIA, and IIX myosin heavy chain (MHC) isoforms. A total of 2,279 feedlot steers weighing 426 ± 6.4 kg were administered no implant or RS on d 0, and fed 0 or 8.3 mg of ZH/kg of diet DM during the last 30 d with a 3-d withdrawal. Treatments were randomly assigned to 24 pens (n = 6 pens/treatment). At slaughter, semimembranosus muscle tissue was excised for RNA isolation from 4 carcasses per pen. No interactions were detected for any of the variables measured in the experiment. Administration of ZH during the last 30 d of the feeding period increased (P < 0.01) ADG, G:F, HCW, and LM area; decreased (P < 0.01) 12th-rib fat depth and marbling; and improved (P < 0.01) yield grade. Treatment had no effect on β1-AR mRNA levels, but there was an increase (P = 0.01) in β2-AR mRNA levels due to ZH inclusion. Myosin heavy chain-I (MHC-I) mRNA levels were unaffected by treatment. For MHC-IIA mRNA concentrations, administration of RS tended (P = 0.08) to increase mRNA levels, whereas ZH feeding the last 30 d tended (P = 0.08) to decrease mRNA levels for this isoform of myosin. Feeding ZH the last 30 d before slaughter increased (P < 0.01) mRNA concentrations of MHC-IIX in semimembranosus muscle of steers. These data indicate the combined use of ZH and RS additively contributes to BW and carcass gain in finishing feedlot steers and decreases marbling scores and USDA quality grades. The LM area increased and fat thickness decreased. In addition, ZH feeding changes the mRNA levels of MHC isoforms to a faster, more glycolytic fiber type in bovine skeletal muscle. These changes in mRNA concentrations of MHC isoforms, due to ZH feeding, could be affecting skeletal muscle hypertrophy.en_US
dc.language.isoengen_US
dc.subjectβ-Adrenergic Agonistsen_US
dc.subjectCattleen_US
dc.subjectImplanten_US
dc.subjectMyosinen_US
dc.subjectZilpaterol Hydrochlorideen_US
dc.titleAdditive effects of a steroidal implant and zilpaterol hydrochloride on feedlot performance, carcass characteristics, and skeletal muscle messenger ribonucleic acid abundance in finishing steersen_US
dc.typeArticleen_US


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