Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
Hegazy, Mohamed-Elamir F.
Mohamed, Tarik A.
Elshamy, Abdelsamed I.
Al-Hammady, Montaser A.
Paré, Paul W. (TTU)
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The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4–5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis.