Sarcoehrenbergilides D-F: Cytotoxic cembrene diterpenoids from the soft coral: Sarcophyton ehrenbergi

Abstract

A solvent extract of the soft coral Sarcophyton ehrenbergi afforded cembrene diterpenoids, sarcoehrenbergilid D-F (1-3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1-3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).

Description

© The Royal Society of Chemistry 2019. cc-by

Keywords

Citation

Hegazy, M.-E.F., Mohamed, T.A., Elshamy, A.I., Hamed, A.R., Ibrahim, M.A.A., Ohta, S., Umeyama, A., Pare, P.W., & Efferth, T.. 2019. Sarcoehrenbergilides D-F: Cytotoxic cembrene diterpenoids from the soft coral: Sarcophyton ehrenbergi. RSC Advances, 9(47). https://doi.org/10.1039/c9ra04158c

Collections