Effect of fractionized exercise on nighttime central blood pressure, cognitive function, and cerebral tissue oxygenation under conditions of normal and long sleep duration
| dc.contributor.committeeChair | Gonzales, Joaquin U. | |
| dc.contributor.committeeMember | Vellers, Heather | |
| dc.creator | Clark, Cayla Evelyn | |
| dc.creator.orcid | 0000-0002-5252-8814 | |
| dc.date.accessioned | 2021-08-03T20:17:41Z | |
| dc.date.available | 2021-08-03T20:17:41Z | |
| dc.date.created | 2021-05 | |
| dc.date.issued | 2021-05 | |
| dc.date.submitted | May 2021 | |
| dc.date.updated | 2021-08-03T20:17:42Z | |
| dc.description.abstract | Elevated blood pressure (BP), particularly central aortic BP, increases the risk for various chronic diseases. The aim of this study was to examine nighttime change in central BP following a day of fractionized exercise when sleep duration was controlled. Since central BP is closely linked to brain health, a secondary aim of this study was to examine relationships between the change in nighttime BP following exercise with indices of cognitive function. Eight healthy middle-aged adults (7 women, aged 46 + 5y) completed three 10-minute bouts of moderate-intensity walking (60-75% age-predicted maximum heart rate) after one week of sleep consisting of normal and long sleep durations (8- and 11-hours time in bed) in a randomized, crossover fashion. Ambulatory BP and cognitive function (Switching, Manikin, Color/Word Stroop) were recorded before and in the morning following the exercise intervention. A 2-way repeated measures ANOVA was used to test for difference in time (before vs. after exercise) or sleep duration (normal vs. long sleep). There was no difference ( P > 0.05) in nighttime peripheral or central BP following fractionized exercise irrespective of sleep duration. We observed a main effect for time for cognitive function such that reaction time, throughput, and correct responses improved for all cognitive tests following fractionized exercise (P < 0.05). The change in nighttime pulse pressure amplification (brachial – central pulse pressure) following exercise was correlated with faster reaction time (r = -0.64, P < 0.01) and higher throughput (r = 0.71, P < 0.01) for the Manikin cognitive test when data from both sleep durations were combined. In summary, our results suggest that fractionized exercise does not significantly change nighttime central BP in healthy middle-aged adults, but it does improve cognitive performance with evidence that interindividual changes in nighttime pulse pressure amplication following exercise is associated with improved cognitive performance. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | https://hdl.handle.net/2346/87488 | |
| dc.language.iso | eng | |
| dc.rights.availability | Access is not restricted. | |
| dc.subject | Blood Pressure | |
| dc.subject | Aortic Pulse Pressure | |
| dc.subject | Fractionized Exercise | |
| dc.subject | Cognitive Function | |
| dc.subject | Cerebral Oxygenation | |
| dc.title | Effect of fractionized exercise on nighttime central blood pressure, cognitive function, and cerebral tissue oxygenation under conditions of normal and long sleep duration | |
| dc.type | Thesis | |
| dc.type.material | text | |
| thesis.degree.department | Health Exercise and Sport Sciences | |
| thesis.degree.discipline | Exercise and Sport Sciences | |
| thesis.degree.grantor | Texas Tech University | |
| thesis.degree.level | Masters | |
| thesis.degree.name | Master of Science |