Anionic Lipid Activation and Allosteric Mechanism of KirBac1.1

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dc.contributor.committeeChairWeber, Joachim
dc.contributor.committeeMemberCozzolino, Anthony
dc.contributor.committeeMemberWylie, Benjamin J.
dc.creatorVersteeg, Derek B.
dc.date.accessioned2023-12-14T22:34:59Z
dc.date.available2023-12-14T22:34:59Z
dc.date.issued2023-08
dc.description.abstractStudy of anionic lipid activation of potassium channel KirBac1.1 through implementation of efflux assays, Solid-State NMR, and coarse-grained molecular dynamics. KirBac1.1 serves as a model system that closely mimics eukaryotic Kir channels. Human Kir channels are linked to heart disease, blood disorders, and neurological disorders. This work aims to improve understanding of Kir channels and their related diseases, aiding in future research and treatments for said diseases.
dc.description.abstractEmbargo status: Restricted until 09/2173. To request the author grant access, click on the PDF link to the left.
dc.format.mimetypeApplication/pdf
dc.identifier.urihttps://hdl.handle.net/2346/97198
dc.language.isoen
dc.rights.availabilityRestricted from online display.
dc.subjectLipids
dc.subjectProteins
dc.subjectBiochemistry
dc.subjectKinetics
dc.subjectAssays
dc.subjectMembranes
dc.subjectPotassium
dc.subjectChannels
dc.titleAnionic Lipid Activation and Allosteric Mechanism of KirBac1.1
dc.typeThesis
thesis.degree.departmentChemistry and Biochemistry
thesis.degree.disciplineBiochemistry
thesis.degree.grantorTexas Tech University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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