Design and Analysis of a Polymeric Left Ventricular Simulator via Computational Modelling

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dc.creatorBaturalp, Turgut Batuhan
dc.creatorBozkurt, Selim
dc.date.accessioned2024-06-18T15:42:37Z
dc.date.available2024-06-18T15:42:37Z
dc.date.issued2024
dc.description© 2024 by the authors. cc-by
dc.description.abstractPreclinical testing of medical devices is an essential step in the product life cycle, whereas testing of cardiovascular implants requires specialised testbeds or numerical simulations using computer software Ansys 2016. Existing test setups used to evaluate physiological scenarios and test cardiac implants such as mock circulatory systems or isolated beating heart platforms are driven by sophisticated hardware which comes at a high cost or raises ethical concerns. On the other hand, computational methods used to simulate blood flow in the cardiovascular system may be simplified or computationally expensive. Therefore, there is a need for low-cost, relatively simple and efficient test beds that can provide realistic conditions to simulate physiological scenarios and evaluate cardiovascular devices. In this study, the concept design of a novel left ventricular simulator made of latex rubber and actuated by pneumatic artificial muscles is presented. The designed left ventricular simulator is geometrically similar to a native left ventricle, whereas the basal diameter and long axis length are within an anatomical range. Finite element simulations evaluating left ventricular twisting and shortening predicted that the designed left ventricular simulator rotates approximately 17 degrees at the apex and the long axis shortens around 11 mm. Experimental results showed that the twist angle is 18 degrees and the left ventricular simulator shortens 5 mm. Twist angles and long axis shortening as in a native left ventricle show it is capable of functioning like a native left ventricle and simulating a variety of scenarios, and therefore has the potential to be used as a test platform.
dc.identifier.citationBaturalp, T.B., & Bozkurt, S.. 2024. Design and Analysis of a Polymeric Left Ventricular Simulator via Computational Modelling. Biomimetics, 9(5). https://doi.org/10.3390/biomimetics9050269
dc.identifier.urihttps://doi.org/10.3390/biomimetics9050269
dc.identifier.urihttps://hdl.handle.net/2346/98587
dc.language.isoeng
dc.subjectleft ventricle
dc.subjectleft ventricular simulator
dc.subjectpneumatic artificial muscle
dc.titleDesign and Analysis of a Polymeric Left Ventricular Simulator via Computational Modelling
dc.typeArticle

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