Review of Biological Effects of Acute and Chronic Radiation Exposure on Caenorhabditis elegans

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dc.creatorDhakal, Rabin (TTU)
dc.creatorYosofvand, Mohammad (TTU)
dc.creatorYavari, Mahsa (TTU)
dc.creatorAbdulrahman, Ramzi
dc.creatorSchurr, Ryan
dc.creatorMoustaid-Moussa, Naima (TTU)
dc.creatorMoussa, Hanna (TTU)
dc.date.accessioned2022-11-30T19:59:09Z
dc.date.available2022-11-30T19:59:09Z
dc.date.issued2021
dc.description© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).en_US
dc.description.abstractKnowledge regarding complex radiation responses in biological systems can be enhanced using genetically amenable model organisms. In this manuscript, we reviewed the use of the nematode, Caenorhabditis elegans (C. elegans), as a model organism to investigate radiation’s biological effects. Diverse types of experiments were conducted on C. elegans, using acute and chronic exposure to different ionizing radiation types, and to assess various biological responses. These responses differed based on the type and dose of radiation and the chemical substances in which the worms were grown or maintained. A few studies compared responses to various radiation types and doses as well as other environmental exposures. Therefore, this paper focused on the effect of irradiation on C. elegans, based on the intensity of the radiation dose and the length of exposure and ways to decrease the effects of ionizing radiation. Moreover, we discussed several studies showing that dietary components such as vitamin A, polyunsaturated fatty acids, and polyphenol-rich food source may promote the resistance of C. elegans to ionizing radiation and increase their life span after irradiation.en_US
dc.identifier.citationDhakal R, Yosofvand M, Yavari M, Abdulrahman R, Schurr R, Moustaid-Moussa N, Moussa H. Review of Biological Effects of Acute and Chronic Radiation Exposure on Caenorhabditis elegans. Cells. 2021; 10(8):1966. https://doi.org/10.3390/cells10081966en_US
dc.identifier.urihttps://doi.org/10.3390/cells10081966
dc.identifier.urihttps://hdl.handle.net/2346/90372
dc.language.isoengen_US
dc.subjectIonizing Radiationen_US
dc.subjectAcute and Chronic Exposureen_US
dc.subjectDoseen_US
dc.subjectBiological Dosimeteren_US
dc.subjectCaenorhabditis elegansen_US
dc.titleReview of Biological Effects of Acute and Chronic Radiation Exposure on Caenorhabditis elegansen_US
dc.typeArticleen_US

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