Comparison of High-Protein, Intermittent Fasting Low-Calorie Diet and Heart Healthy Diet for Vascular Health of the Obese

dc.creatorZuo, Li
dc.creatorHe, Feng
dc.creatorTinsley, Grant M. (TTU)
dc.creatorPannell, Benjamin K.
dc.creatorWard, Emery
dc.creatorArciero, Paul J.
dc.date.accessioned2023-01-27T17:04:13Z
dc.date.available2023-01-27T17:04:13Z
dc.date.issued2016
dc.description© 2016 Zuo, He, Tinsley, Pannell, Ward and Arciero. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.en_US
dc.description.abstractAim: It has been debated whether different diets are more or less effective in long-term weight loss success and cardiovascular disease prevention among men and women. To further explore these questions, the present study evaluated the combined effects of a high-protein, intermittent fasting, low-calorie diet plan compared with a heart healthy diet plan during weight loss, and weight loss maintenance on blood lipids and vascular compliance of obese individuals. Methods: The experiment involved 40 obese adults (men, n = 21; women, n = 19) and was divided into two phases: (a) 12-week high-protein, intermittent fasting, low-calorie weight loss diet comparing men and women (Phase 1) and (b) a 1-year weight maintenance phase comparing high-protein, intermittent fasting with a heart healthy diet (Phase 2). Body weight, body mass index (BMI), blood lipids, and arterial compliance outcomes were assessed at weeks 1 (baseline control), 12 (weight loss), and 64 (12 + 52 week; weight loss maintenance). Results: At the end of weight loss intervention, concomitant reductions in body weight, BMI and blood lipids were observed, as well as enhanced arterial compliance. No sex-specific differences in responses were observed. During phase 2, the high-protein, intermittent fasting group demonstrated a trend for less regain in BMI, low-density lipoprotein (LDL), and aortic pulse wave velocity than the heart healthy group. Conclusion: Our results suggest that a high-protein, intermittent fasting and low-calorie diet is associated with similar reductions in BMI and blood lipids in obese men and women. This diet also demonstrated an advantage in minimizing weight regain as well as enhancing arterial compliance as compared to a heart healthy diet after 1 year.en_US
dc.identifier.citationZuo L, He F, Tinsley GM, Pannell BK, Ward E and Arciero PJ (2016) Comparison of High-Protein, Intermittent Fasting Low-Calorie Diet and Heart Healthy Diet for Vascular Health of the Obese. Front. Physiol. 7:350. doi: 10.3389/fphys.2016.00350en_US
dc.identifier.urihttps://doi.org/10.3389/fphys.2016.00350
dc.identifier.urihttps://hdl.handle.net/2346/90486
dc.language.isoengen_US
dc.subjectArterial Complianceen_US
dc.subjectCholesterolen_US
dc.subjectLipidsen_US
dc.subjectWeight Lossen_US
dc.subjectWeight Relapseen_US
dc.titleComparison of High-Protein, Intermittent Fasting Low-Calorie Diet and Heart Healthy Diet for Vascular Health of the Obeseen_US
dc.typeArticleen_US

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