Positive selection and gene expression analyses from salivary glands reveal discrete adaptations within the ecologically diverse bat family phyllostomidae

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dc.creatorVandewege, Michael W. (TTU)
dc.creatorSotero-Caio, Cibele G. (TTU)
dc.creatorPhillips, Caleb D. (TTU)
dc.date.accessioned2023-05-01T14:48:30Z
dc.date.available2023-05-01T14:48:30Z
dc.date.issued2020
dc.description© The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. cc-by-nc
dc.description.abstractThe leaf-nosed bats (Phyllostomidae) are outliers among chiropterans with respect to the unusually high diversity of dietary strategies within the family. Salivary glands, owing to their functions and high ultrastructural variability among lineages, are proposed to have played an important role during the phyllostomid radiation. To identify genes underlying salivary gland functional diversification, we sequenced submandibular gland transcriptomes from phyllostomid species representative of divergent dietary strategies. From the assembled transcriptomes, we performed an array of selection tests and gene expression analyses to identify signatures of adaptation. Overall, we identified an enrichment of immunity-related gene ontology terms among 53 genes evolving under positive selection. Lineage-specific selection tests revealed several endomembrane system genes under selection in the vampire bat. Many genes that respond to insulin were under selection and differentially expressed genes pointed to modifications of amino acid synthesis pathways in plant-visitors. Results indicate salivary glands have diversified in various ways across a functional diverse clade of mammals in response to niche specializations.
dc.identifier.citationVandewege, M.W., Sotero-Caio, C.G., & Phillips, C.D.. 2020. Positive selection and gene expression analyses from salivary glands reveal discrete adaptations within the ecologically diverse bat family phyllostomidae. Genome Biology and Evolution, 12(8). https://doi.org/10.1093/GBE/EVAA151
dc.identifier.urihttps://doi.org/10.1093/GBE/EVAA151
dc.identifier.urihttps://hdl.handle.net/2346/93052
dc.language.isoeng
dc.subjectChiroptera
dc.subjectImmunity
dc.subjectMolecular evolution
dc.subjectSelection
dc.subjectSubmandibular glands
dc.titlePositive selection and gene expression analyses from salivary glands reveal discrete adaptations within the ecologically diverse bat family phyllostomidae
dc.typeArticle

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