Determination of phosphite (HPO3−2) by a new IC/MS/MS method using an 18O-labeled HPO3−2 internal standard

dc.creatorSadeghi, Sepideh (TTU)
dc.creatorAnderson, Todd A. (TTU)
dc.creatorJackson, W. Andrew (TTU)
dc.date.accessioned2022-12-02T17:35:34Z
dc.date.available2022-12-02T17:35:34Z
dc.date.issued2021
dc.description© 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.description.abstractA new method has been developed to determine trace amounts of phosphite (HPO3−2) in environmental samples using ion chromatography with electrospray tandem mass spectrometry (IC-ESI/MS/MS). The method includes the production and use of an 18O-labeled HPO3−2 internal standard (IS). This isotopically labeled IS significantly improved sensitivity and could account for matrix suppression. The method detection limit (MDL) was determined as 0.017 and 0.034 μg L−1 of HPO3−2 (6.5 and 13 ng P L−1) using a 500 and 25 μL injection loop, respectively. Precision (1–10%) and accuracy (recoveries = 96–106%) were established for a range of environmental samples using known (spiked) addition. The impact of ionic interferences was investigated by evaluating the response of the internal standard in the presence of common anions with respect to distilled deionized water. The most significant interference was due to nitrate (100 mg-NO3− L−1) with a 99.99% reduction in IS intensity. The method was successfully applied to wastewater effluent, surface water, tap water, and soil samples. Relatively low concentrations <0.25 μg HPO3−2 L−1 were measured in tap water, surface water and wastewater effluent, and ~1.6 μg kg−1 HPO3−2 in soil samples, using both injection loops. Limited suppression was observed for all matrices. The largest IS peak area suppression (~98%) was observed in WW effluent with 500 μL injection loop; however, this method was able to quantify HPO3−2 with good recoveries and precision despite the mentioned suppression, supporting the ability of theen_US
dc.identifier.citationSadeghi, S., Anderson, T. A., & Jackson, W. A. (2021). Determination of phosphite (HPO3−2) by a new IC/MS/MS method using an 18O-labeled HPO3−2 internal standard. Talanta, 230, 122198. https://doi.org/10.1016/j.talanta.2021.122198en_US
dc.identifier.urihttps://doi.org/10.1016/j.talanta.2021.122198
dc.identifier.urihttps://hdl.handle.net/2346/90398
dc.language.isoengen_US
dc.subjectPhosphiteen_US
dc.subjectIC/MS/MSen_US
dc.subjectInternal Standarden_US
dc.titleDetermination of phosphite (HPO3−2) by a new IC/MS/MS method using an 18O-labeled HPO3−2 internal standarden_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
sadeghi_article.pdf
Size:
771.26 KB
Format:
Adobe Portable Document Format
Description:
Main article with TTU Libraries cover page

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.57 KB
Format:
Item-specific license agreed upon to submission
Description:

Collections